N-Cholinomimetics and N-Cholinoblockers








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Nicotine and its derivatives, such as lobeline and cytisine, are N-cholinomimetics that interact with nicotinic cholinoceptors. They have a two-phase action, initially exciting and then inhibiting these receptors. Nicotine, derived from tobacco leaves, is used in experimental pharmacology and affects both peripheral and central N-cholinoceptors.